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By the author of the bestseller THE MIRACULOUS RESULTS OF EXTREMELY HIGH DOSES OF THE SUNSHINE HORMONE VITAMIN D3 MY EXPERIMENT WITH HUGE DOSES OF D3 FROM 25,000 to 50,000 to 100,000 IU A Day OVER A 1 YEAR PERIOD
The author shares the amazing secrets of a lifetime of high-dose melatonin experiments on himself and others!
Extreme Dose! Melatonin The Miracle Anti-Aging Hormone Anti-Alzheimer’s Hormone Anti-Baldness Hormone Menopause Reversal Hormone Jeff T. Bowles Extreme Dose! Melatonin The Miracle Anti-Aging Hormone Anti-Alzheimer’s Hormone Anti-Baldness Hormone Menopause Reversal Hormone book Box
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Papvasiliou PS, Cotzias GC, Duby SE, Steck AJ, Bell M, Lawrence WHPreliminary evidence suggests that melatonin may play a role in pain modulation and digestive functionHalf of them took 3mg MEL and half of them Placebo at bedtime (10-12p.m.) in a fully randomized and double-blind fashionBazil CW, Short D, Crispin D, Zheng WCytoprotection by melatonin and growth hormone in early rat myocardial infarction as revealed by Feulgen DNA staining12th edNordlund JJ, Lerner ABFriedman M, Green MF, Sharland DEClin Endocrinol
Melatonin in clinical oncologyCell Mol Life Sci2000;7(2):347-51.Motta E, Czuczwar SJ, Ostrowska Z, et al1981; 52: 269-279[PubMed]58follows rigorous standards of quality and accountabilityNeurologyMelatonin: a contraceptive for the ninetiesPeri- or postmenopausal women who use melatonin supplements should do so only for a short period of time since long-term effects are not known.Benzodiazepine WithdrawalSome research suggests that melatonin may help elderly people with insomnia who are tapering off or stopping benzodiazepines such as diazepam (Valium), alprazolam (Xanax), or lorazepam (Ativan)
A review of the scientific literature suggests that melatonin supplements may help prevent jet lag, particularly in people who cross 5 or more time zones.A few clinical studies suggest that, when taken for short periods of time (days to weeks), melatonin is more effective than a placebo in reducing the time it takes to fall asleep, increasing the number of sleeping hours, and boosting daytime alertnessMelatonin can produce immunoenhancement in Japanese quail (Coturnix coturnix japonica) without prior immunosuppression[PubMed]152This regimen resulted in stabilization of the disease and improved quality of life for about 40% of the recipients. The antiproliferative and proapoptotic actions of melatonin on experimental colon carcinoma are probably mediated by melatonin MT(1) and MT(2) receptors.In another study, melatonin 10–50 mg daily at 8 pm potentiated IL-2 immunotherapy of pulmonary metastases. As with melatonin therapy in patients with AIDS, the study encouraged treatment periods of 3–4 weeks with a 1-week washout.Melatonin injections have been found to stimulate tumor growth if given in the morning, have no effect when given in midafternoon, and have a retarding effect in the evening.[45,46]Some have suggested that melatonin be administered to patients at earlier stages of cancer, in parallel with standard oncologic treatment regimens. However, some questions remain concerning the anticancer effects of melatonin, and data from stringent, large, randomized clinical trials are required before melatonin can be universally accepted as an anticancer drugEntrainment of free-running circadian rhythms by melatonin in blind peoplePhiladelphia, PA: Elsevier Saunders; 2011.Morceli G, Honorio-Franca AC, Fagundes DL, Calderon IM, Franca EL
2002; 293: 1114-11231987; 22: 205-212A study of 5 patients with cardiac syndrome X found that nocturnal melatonin levels were markedly reduced.Gastrointestinal SystemGastroprotective effects of melatonin have been observed in various models of gastric ulcers at several laboratories, including ours.[111–113] These effects may also be related to the antioxidant effects of melatoninMyocardial ischemia-reperfusion in rats: reduction of infarct size by either supplemental physiological or pharmacological doses of melatonin[PubMed]149
Melatonin as an effective protector against doxorubicin-induced cardiotoxicity[PubMed]108NCBISkip to main contentSkip to navigationResourcesAll ResourcesChemicals & BioassaysBioSystemsPubChem BioAssayPubChem CompoundPubChem Structure SearchPubChem SubstanceAll Chemicals & Bioassays Resources.DNA & RNABLAST (Basic Local Alignment Search Tool)BLAST (Stand-alone)E-UtilitiesGenBankGenBank: BankItGenBank: SequinGenBank: tbl2asnGenome WorkbenchInfluenza VirusNucleotide DatabasePopSetPrimer-BLASTProSplignReference Sequence (RefSeq)RefSeqGeneSequence Read Archive (SRA)SplignTrace ArchiveUniGeneAll DNA & RNA Resources.Data & SoftwareBLAST (Basic Local Alignment Search Tool)BLAST (Stand-alone)Cn3DConserved Domain Search Service (CD Search)E-UtilitiesGenBank: BankItGenBank: SequinGenBank: tbl2asnGenome ProtMapGenome WorkbenchPrimer-BLASTProSplignPubChem Structure SearchSNP Submission ToolSplignVector Alignment Search Tool (VAST)All Data & Software Resources.Domains & StructuresBioSystemsCn3DConserved Domain Database (CDD)Conserved Domain Search Service (CD Search)Structure (Molecular Modeling Database)Vector Alignment Search Tool (VAST)All Domains & Structures Resources.Genes & ExpressionBioSystemsDatabase of Genotypes and Phenotypes (dbGaP)E-UtilitiesGeneGene Expression Omnibus (GEO) Database Gene Expression Omnibus (GEO) DatasetsGene Expression Omnibus (GEO) ProfilesGenome WorkbenchHomoloGeneMap ViewerOnline Mendelian Inheritance in Man (OMIM)RefSeqGeneUniGeneAll Genes & Expression Resources.Genetics & MedicineBookshelfDatabase of Genotypes and Phenotypes (dbGaP)Genetic Testing RegistryInfluenza VirusMap ViewerOnline Mendelian Inheritance in Man (OMIM)PubMedPubMed Central (PMC)PubMed Clinical QueriesRefSeqGeneAll Genetics & Medicine Resources.Genomes & MapsDatabase of Genomic Structural Variation (dbVar)GenBank: tbl2asnGenomeGenome ProjectGenome ProtMapGenome WorkbenchInfluenza VirusMap ViewerNucleotide DatabasePopSetProSplignSequence Read Archive (SRA)SplignTrace ArchiveAll Genomes & Maps Resources.HomologyBLAST (Basic Local Alignment Search Tool)BLAST (Stand-alone)BLAST Link (BLink)Conserved Domain Database (CDD)Conserved Domain Search Service (CD Search)Genome ProtMapHomoloGeneProtein ClustersAll Homology Resources.LiteratureBookshelfE-UtilitiesJournals in NCBI DatabasesMeSH DatabaseNCBI HandbookNCBI Help ManualNCBI News & BlogPubMedPubMed Central (PMC)PubMed Clinical QueriesPubMed HealthAll Literature Resources.ProteinsBioSystemsBLAST (Basic Local Alignment Search Tool)BLAST (Stand-alone)BLAST Link (BLink)Conserved Domain Database (CDD)Conserved Domain Search Service (CD Search)E-UtilitiesProSplignProtein ClustersProtein DatabaseReference Sequence (RefSeq)All Proteins Resources.Sequence AnalysisBLAST (Basic Local Alignment Search Tool)BLAST (Stand-alone)BLAST Link (BLink)Conserved Domain Search Service (CD Search)Genome ProtMapGenome WorkbenchInfluenza VirusPrimer-BLASTProSplignSplignAll Sequence Analysis Resources.TaxonomyTaxonomyTaxonomy BrowserTaxonomy Common TreeAll Taxonomy Resources.Training & TutorialsNCBI Education PageNCBI HandbookNCBI Help ManualNCBI News & BlogAll Training & Tutorials Resources.VariationDatabase of Genomic Structural Variation (dbVar)Database of Genotypes and Phenotypes (dbGaP)Database of Single Nucleotide Polymorphisms (dbSNP)SNP Submission ToolAll Variation Resources.How ToAll How ToChemicals & BioassaysDNA & RNAData & SoftwareDomains & StructuresGenes & ExpressionGenetics & MedicineGenomes & MapsHomologyLiteratureProteinsSequence AnalysisTaxonomyTraining & TutorialsVariationAbout NCBI AccesskeysMy NCBISign in to NCBISign OutKaptanoglu E, Palaoglu S, Demirpence E, Akbiyik F, Solaroglu I, Kilinc ABartsch C, Bartsch H, Fluchter St H, Lippert TH[PubMed]46For many of my patients, taking hormones at a low physiological dose along with other lifestyle changes is the answer to their prayersThe therapeutic potential of melatonin: a review of the science 171bf2437f